| To study the effects of drought on grain starch contents and activities of related key enzymes and minimize damages caused by drought after anthesis in spring wheat, two spring wheat cultivars, Ningchun 4 and Ningchun 47, were used in a pot experiment by manipulating the post-anthesis soil moisture. The results showed that the starch contents of Ningchun 4 and Ningchun 47 became decreased significantly under drought stress after anthesis. The amylase, amylopectin, and total starch contents were decreased by 9.78%～30.07%, 9.02%～19.92% and 9.25%～22.82%, respectively. The activities of ADPG-PPase, UDPG-PPase, SSS, SBE and the quality of spring wheat grains were also decreased. Therefore, implementation of proper cultivation techniques remitting damages from drought after anthesis could improve the yield and the quality of spring wheat. |